Prestegard Lab

Publication Highlight


Structural Aspects of Heparan Sulfate Binding to Robo1-Ig1-2

Qi Gao, Cheng-Yu Chen, Chengli Zong, Shuo Wang, Annapoorani Ramiah, Pradeep Prabhakar, Laura C. Morris, Geert-Jan Boons, Kelly W. Moremen and James H. Prestegard.
ACS Chemical Biology (2016) 11:3106-3113.     (doi:10.1021/acschembio.6b00692)

Robo1-HS-Slit2

Model of the complex of Robo1-IG1-2 (blue), heparan sulfate octamer (beige) and Slit2 (green) with positive protein residues labeled in red.